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Rezensionsartikel

Outcomes of Osteoarthritis after Bariatric Surgery

Lan Vu, Noah J. Switzer, D?Arcy C. Durand, Douglas Hedden and Shahzeer Karmali

Joint Osteoarthritis (OA) is a major source of morbidity and disability in the aging population. It is especially a concern to overweight individuals, as obesity is an important..Mehr sehen»

Fallbericht

A Case of Lichen Planus-Lupus Erythematous Overlap Syndrome with Tuberculosis

Arpita Arghya

A 36-year-old lady presented with persistent erythematous lesions eventually became pigmented over duration of 2 months. Her clinical features, histopathology, immunofluorescenc..Mehr sehen»

Forschungsartikel

Discovery of Phosphonic Acid-Containing Desaminobenzimidazoles as Fructose 1,6-Bisphosphatase Inhibitors that are Suitable for Oral Delivery via Prodrugs

Qun Dang, K. Raja Reddy, Srinivas Rao Kasibthatla, Tao Jiang, Frank Taplin, Tony Gibson, Scott C. Potter6, Paul D. van Poelje, M. Rami Reddy and Mark D. Erion

To discover an alternative series of fructose 1,6-bisphosphatase (FBPase) inhibitors that is suitable for oral delivery via prodrugs, the 4-amino group was removed from the ini..Mehr sehen»

Forschungsartikel

Effects of Alpha-Lipoic Acid on Oxidative Stress and Kinin Receptor Expression in Obese Zucker Diabetic Fatty Rats

Adil El Midaoui, Sebastien Talbot, Karim Lahjouji, Jenny Pena Dias, I. George Fantus and Rejean Couture

Objective: To investigate the impact of alpha-lipoic acid on superoxide anion production and NADPH oxidase activity as well as on the expression of kinin B1 and B2 receptors in ..Mehr sehen»

Rezensionsartikel

Enigmatic Biomolecules from the Mitochondrial Genome

Gabriel D Dakubo

The mitochondrion is the only eukaryotic organelle with its semi-autonomously controlled genome. The minuscule nature of this genome does not undermine the importance of its pro..Mehr sehen»

Kleiner Rückblick

Mesenchymal Stem Cells As A Therapeutic Option For Patients With ALS

Dariusz Boruczkowski, Dominika Gładysz, Mariusz Grudniak, Karol Kosterna and Katarzyna Pawelec

It has been postulated that mesenchymal stem cells could play a role in treatment of patients with amyotrophic lateral sclerosis. Variety of mechanism behind MSC action has been..Mehr sehen»