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Forschungsartikel

Plasma Aldosterone Level in Metabolic Syndrome Patients Compared with Individuals without Metabolic Syndrome. A Survey on Iranian Population

Abdolamir Atapour, Ali akbar Vosoughi, Azizollah Abadi, Ali Kachouei, Masoumeh Sadeghi, Diana Taheri and Shahaboddin Dolatkhah

Background: previous studies showed the role of aldosterone in pathogenesis of metabolic syndrome. The aim of this study was analys..Mehr sehen»

Fallbericht

Thalidomide, A Rational Agent for Treatment of Multicentric Reticulohistiocytosis

Daniel J Zinn, Olive Eckstein, Mary L Olsen, Carl E Allen and Kenneth L McClain

A patient with Multifocal Reticulohistiocytosis (MRH) of skin and joints failed treatment with etanercept, methotrexate, hydroxychloroquine, prednisone, bisphosphonates and hydr..Mehr sehen»

Forschungsartikel

Assessment of Left Atrial Functions in Patients with Prediabetes

Oyku Gulmez, Hulya Parıldar, Ozlem Cigerli, Nilgün Guvener Demirag

Background: LA volumes and functions are reported to be independent predictors of cardiovascular events in general and diabetic population. The aim of this is to evaluate the ef..Mehr sehen»

Forschungsartikel

Is There A Relationship Between Visfatin Level and Type 2 Diabetes Mellitus In Obese And Non Obese Patients?

Eid M El-Shafey, Gamal F El-Naggar, Mohamed M Al-Bedewy and Hesham El-Sorogy

Background: Visfatin is a newly discovered cytokine that is highly expressed in visceral fat with a direct relationship to type 2 diabetes mellitus (T2DM). The present study was..Mehr sehen»

Forschungsartikel

Targeting of Calcitriol to Inflammatory Breast Cancer Tumors and Metastasis In Vitro and In Vivo

Rachel J Schaefer, Rebecca Russell, Hemanth Akkiraju1, Jeremy C Bonor, Kenneth L van Golen1, and Anja Nohe1*

Inflammatory Breast Cancer (IBC) is arguably the most severe form of breast cancer with a very high mortality rate. IBC is distinct from other forms of breast cancer expressing ..Mehr sehen»

Forschungsartikel

Exhaustive Characterization of TCR–pMHC Binding Energy Estimated by the String Model and Miyazawa-Jernigan Matrix

Hiromichi Tsurui, Takuya Takahashi, Yuko Matsuda, Qingshun Lin, Aya Sato-Hayashizaki and Sachiko Hirose

Accurate calculations of protein–protein binding free energies based on rigorous models, which consider the binding complex structure in atomic detail, are computationally expens..Mehr sehen»