PGC-1α and p38 MAPK are involved in uncoupling protein 2-dependent reactive oxygen species production in renal tubular epithelial cells

Xiaolei Chen, Xiaoyu Xie, Siyu Duan, Chunlai Nie*

Object: The objective was to investigate Uncoupling protein 2 (UCP2)-dependent Reactive oxygen species (ROS) production in renal tubular epithelial cells tre..Mehr sehen»

Thalidomide, A Rational Agent for Treatment of Multicentric Reticulohistiocytosis

Daniel J Zinn, Olive Eckstein, Mary L Olsen, Carl E Allen and Kenneth L McClain

A patient with Multifocal Reticulohistiocytosis (MRH) of skin and joints failed treatment with etanercept, methotrexate, hydroxychloroquine, prednisone, bisphosphonates and hydr..Mehr sehen»

A Novel Validation Strategy for Next Generation Sequencing Mutation Profiling in FFPE Tissues

Ken CN Chang, Gladys Arreaza, John Kang, Maureen Maguire, Ping Qiu and Matthew J Marton

Abstract

We previously developed a “concordance calculator” to quantify reproducibility of multi-variant calls among next generation sequencing (NGS) sampl..Mehr sehen»

Gene-Gene Interaction Mapping Of Human Cytomegalic Virus through System Biology Approach

Navrati Saxena, Vijaylaxmi Saxena, Supriya Dixit and Alfisha Ashraf

Systems biology is concerned with the study of biological systems, by investigating the components of cellular networks and their interactions. The objective of present study is..Mehr sehen»

Diabetic Neuropathy: Patients' Experiences and Perceptions: A Qualitative Study in Type 2 Diabetics

Dr. Ibrahim El Bayoumy

Background: Diabetic neuropathy is a serious complication of diabetes mellitus, it is a result from micro vascular injury that involves small blood vessels supp..Mehr sehen»

Dermatology: An Opinion

Shirley Aston

Dermatology involves but is not li..Mehr sehen»