A Novel Validation Strategy for Next Generation Sequencing Mutation Profiling in FFPE Tissues

Ken CN Chang, Gladys Arreaza, John Kang, Maureen Maguire, Ping Qiu and Matthew J Marton

Abstract

We previously developed a “concordance calculator” to quantify reproducibility of multi-variant calls among next generation sequencing (NGS) sampl..Mehr sehen»

Association of a 27-Bp Repeat Polymorphism in Intron 4 of Endothelial Constitutive Nitric Oxide Synthase Gene with Coronary Artery Disease in a Tunisian Population

Letaief Afef*, Benothmane Leila, Charfeddine Bassem, Ennez Hajri Samia, Guider Jridi and Limem Khalifa

Background: Nitric oxide (NO) plays a major role in the regulation of vascular tone associations between NO genotypes. Coronary artery disease (CAD) and other r..Mehr sehen»

Outcome after Fluoroscopic Guided Closed Reduction and Percutaneous Kirschner Wire Fixation of Lisfranc Joint Injuries

Shamim Ahmad Bhat, Khurshid Ahmad Kangoo, Adnan Zahoor, Rameez Raja and Sami Jain

Twenty patients of Lisfranc joint injuries managed by flouroscopic guided closed reduction and percutaneous K-Wire fixation were evaluated for functional results with average fo..Mehr sehen»

Comparative Study of the Clinical Outcome of Retrograde Laparoscopic Appendicectomy Using a Single Polymer Clip for Complicated Versus for Non-Complicated Appendicitis

Basem Mohamed Sieda *

Objective To evaluate the clinical outcome of using single Hem-O-Lock polymer clip and compare technical feasibility of retrograde laparoscopic appendicectomy for complicated v..Mehr sehen»

Serum Metabonomic Study of 2 Uyghur Probable MODY Families Based on 1H NMR

Aierken Taxitiemuer, Ylilihamujiang Yimamu, Patamu Mohemaiti and Rebiya Nuli

Objective: To study the characteristics of changes in serum metabolites in two Uyghur families with probable maturity-onset diabetes of young (MODY). Method: We..Mehr sehen»

Hormone Therapy for Cancer Treatment

Nandan Gupta*, Rishabha Malviya

Cancer treatment which is processes by using different types of hormones that further inhibit or stops the growth of malignancy. Hormone therapy is also known by different names..Mehr sehen»